Biochemistry

Latest news from the Biochemistry department

Update on Vitamin D Analysis 5/10/2015

on Monday, 05 October 2015. Posted in Biochemistry

Update on Vitamin D Analysis 5/10/2015

The vitamin D equipment is now fixed and operational. We have now started working through our backlog. We estimate that our backlog is approx 21 days. If you require any further infomation, please contact the laboratory.

Delay in Vitamin D Analysis

on Monday, 14 September 2015. Posted in Blood Sciences, Biochemistry

Delay in Vitamin D Analysis

Date of update: 14/9/2015

We are experiencing a short delay in the processing and reporting of Vitamin D requests.

We hope to have this situation resolved in the next week and will be working through our backlog as quickly as possible. We will keep updating the web site with our progress.

This is due to problems with the equipment which we are working to resolve as soon as possible. 

If you would like to discuss this further or expedite the measurement of request please contact the duty biochemist on bleep 2506 or at This email address is being protected from spambots. You need JavaScript enabled to view it.

Change to Thyroid requesting

on Thursday, 29 May 2014. Posted in Blood Sciences, Biochemistry

Change to Thyroid requesting

As of 27th May 2014 TSH only will be the frontline test for investigating Thyroid function. If the TSH is <0.35 mU/L or >4.9 mU/L a fT4 will be automatically added on to the request. If the TSH is <0.1 mU/L fT3 will also be added. The reason for this is to encourage more appropriate use of the thyroid tests. If you have any queries or concerns please contact the duty biochemist (bleep 2506).

PTH Update

on Tuesday, 04 March 2014. Posted in Blood Sciences, Biochemistry

PTH Update

From 27th February 2014 we will be resuming a PTH service from Heartlands using the Roche intact PTH assay (iPTH).  It is difficult to directly compare results determined from the previous Abbott assay to the Roche assay as the Abbott method had a significant positive bias with respect to Roche, therefore you should expect slightly lower results now.  The reference range for iPTH on the Roche assay is 1.6-6.9 pmol/L. 

 

Analysis will be batched daily, Monday-Friday.  As previously plasma from EDTA samples is the preferred sample type.  If there is a need for an urgent PTH the current process of contacting the duty biochemist/duty consultant will continue and the urgent pathway implemented. If there are any queries clinicians should contact the duty biochemist/duty consultant.

New Laboratory

on Saturday, 31 August 2013. Posted in Haematology, Biochemistry, General

New Laboratory

A video of the new laboratory at Birmingham Heartlands Hospital

New Testosterone Assay - For use in males

on Tuesday, 30 July 2013. Posted in Biochemistry

New Testosterone Assay - For use in males

The testosterone assay for male patients will be changing the week starting 5th August 2013. This is due to a re-formulation of the reagent by the manufacturer. There will be a change in the reference post-change:

4.9 – 32.0 nmol/L

A comment will be appended to all reports for a short period of time once the assay change has occurred.

Prolactin Assay Change

on Wednesday, 20 March 2013. Posted in Biochemistry, General

The prolactin assay will be changing in the next few weeks. This is because it has been re-standardised by the manufacturer.

The new assay gives results approximately 25% lower than what is currently reported. 

EDTA Tube required for PTH analysis

on Wednesday, 23 January 2013. Posted in Biochemistry

EDTA Tube required for PTH analysis

EDTA tubes are now the only accepted tube type for PTH analysis

Update on Vitamin D analysis

on Tuesday, 15 September 2015. Posted in Blood Sciences, Biochemistry

update: 15/09/2015

Update on Vitamin D analysis

The vitamin D equipment is now fixed and operational. We have now started working through our backlog. We estimate that our backlog is approx 28 days. If you require any further infomation, please contact the laboratory.

Notification of changes to CA19-9

on Tuesday, 10 June 2014. Posted in Blood Sciences, Biochemistry

On Wednesday 11th June the method for the CA19-9 assay at HEFT will change from the Siemens Immulite assay to the Roche assay. Our comparisons have shown that the results are comparable in most cases; however, there were some samples which did show a poor correlation.  We are therefore going to dual report results for a period to allow transition of serially monitored patients to the new CA199 assay.

Further more detailed information is available on request. If you have any queries or comments please contact Craig Webster (Clinical Lead for Blood Sciences) by email or ext 42930.

Laboratory Information System Migration

on Thursday, 29 May 2014. Posted in Blood Sciences, Microbiology, Cellular Pathology, Haematology, Immunology, Biochemistry, General

Laboratory Information System Migration
In order to bring systems in line with the restructured laboratory services the Laboratory Medicine directorate will be migrating to new Laboratory Information System Databases for Blood Sciences and Microbiology.
 
The migration is due to commence at 8am Monday 2nd June.
 
No downtime is anticipated but there may be some temporary disruption as the migration progresses.
 
The Blood Sciences System will replace what is currently the separate disciplines of Chemistry, Haematology and Immunology as a single department. As such the ICE Reporting System will display reports as Blood Sciences (Orange highlighting).

Important Notice re PTH analysis

on Friday, 14 February 2014. Posted in Blood Sciences, Biochemistry

Abbott Diagnostics withdraws PTH assay with Immediate Effect

Important Notice re PTH analysis
Dear Colleague,

Product Recall: Parathyroid hormone (PTH) test

Abbott Laboratories who supply our major laboratory biochemistry analysers and the reagents for the majority of the tests we run on these machines, have issued a global product recall for their parathyroid hormone (PTH) test. We received an initial warning of this recall by phone on 13th February and written confirmation and further details this morning. We have been instructed to stop using their PTH assay immediately and destroy our current stocks of reagent.

New AFP Assay in use from 9th August 2013

on Friday, 09 August 2013. Posted in Biochemistry, General

New AFP Assay in use from 9th August 2013
New method for AFP as of 9th August 2013 with extended dynamic range to 167,660 iU/mL.  Please contact the duty biochemist (bleep 2506) if you wish to discuss this further.
 
The reference range for the new assay is 0.7-7.3 iu/L

Persistently Elevated LFTs and What to Do

on Tuesday, 02 April 2013. Posted in Biochemistry

Persistently Elevated LFTs and What to Do

A podcast on the interpretation of LFTs

Data visualisation talk - Craig Webster

on Friday, 01 March 2013. Posted in Biochemistry

Data visualisation talk - Craig Webster

Data visualisation talk, exploring methodologies and examples of visualisation of large datasets

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The laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital form part of the services provided by University Hospitals Birmingham and are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link: https://www.ukas.com/find-an-organisation/

  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217
  • United Kingdom Health Security Agency laboratory is a UKAS accredited medical laboratory No.8213

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database: http://www.heftpathology.com/frontpage/test-database.html.

Protection of personal information - Laboratory Medicine comply with the Trust Data Protection policy and have procedures in place to allow the Directorate and its employees to comply with the Data Protection act  1998 and associated best practice and guidance.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235

UKAS HEFT