First Class Post to reference laboratory
No special requirements for transporting sample to the laboratory
Lithium heparin plasma
store frozen prior to shipment to referral laboratory
7-dehydrocholesterol is a precursor of cholesterol biosynthesis. Elevated levels of 7-dehydrocholesterol and low levels of cholesterol are found in patients with Smith Lemli Opitz (SLO) syndrome. This is an autosomal recessive disorder characterised by dysmorphic features with abnormalities of limbs and genitalia. The primary defect in SLO is presumed to be due to a deficiency of delta-7-dehydrocholesterol reductase. Measurement of 7-dehydrocholesterol is particularly important in patients suspected of having SLO when cholesterol levels are low-normal, as high levels of 7-dehydrocholesterol may interfere with cholesterol assays.
Provided by Reference Laboratory
The laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital form part of the services provided by University Hospitals Birmingham and are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link: https://www.ukas.com/find-an-organisation/
Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.
For further test information, please visit the test database: http://www.heftpathology.com/frontpage/test-database.html.
For further information contact Louise Fallon, Quality Manager, 0121 424 1235