Preferred Sample Type

Alanine Aminotransferase (ALT)

Suitable Specimen Types

  • Serum
  • Li Hep Plasma
0.2 mL blood (Paediatric minimum volume is 30 uL)

Specimen Transport

Not applicable

Sample Processing in Laboratory

No special requirements

Sample Preparation

Centrifuge on arrival

Turnaround Time

1 day

Sample Stability

4 ºC

Alanine Aminotransferase (ALT)

General Information

Alanine aminotransferase (glutamate pyruvate transaminase) belongs to the transaminases, which catalyse the interconversion of amino acids and a-ketoacids by transfer of amino groups.

Elevated levels of the transaminases can indicate myocardial infarction, hepatic disease, muscular dystrophy and organ damage.  However, serum elevations of ALT activities are rarely observed except in parenchymal liver disease, since ALT is a more liver-specific enzyme than AST.

Patient Preparation



None Given

Reference Range

0-55 IU/L

Source of Reference Range

Abbott Diagnostics


  • EQA Scheme?: Yes
  • EQA Status:

    UK NEQAS for Clinical Chemistry Scheme

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Protection of Personal Information – Laboratory Medicine comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

The Trust Laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital were awarded UKAS (United Kingdom Accreditation Service) accreditation to the internationally recognised ISO 15189 standard in May 2015. For a list of accredited tests and other information please visit the test database
Tests not appearing on this scope are either under consideration or in the process of accreditation and so currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235