Department

Biochemistry

Preferred Sample Type

Follicle Stimulating Hormone (FSH)

Suitable Specimen Types

  • Serum
5-10 mL vacutainer (minimum sample volume 70 uL)

Sample Processing in Laboratory

Usual

Sample Preparation

Centrifuge

Turnaround Time

1 day

Sample Stability

Serum or plasma treated with heparin or EDTA may be used. Samples should be clot-free and free of red blood cells or other particulate matter.

The presence of fibrin may cause erroneous results. If testing is delayed, store at 2-8˚C for up to 14 days. For longer periods, store serum frozen at -20˚C.

 

Follicle Stimulating Hormone (FSH)

General Information

Follicle Stimulating Hormone (FSH), like Luteinising Hormone (LH), belongs to the gonadotropin family. They synergistically regulate and stimulate the growth and function of the ovaries and testes.

FSH and LH are released in pulses from the gonadotrophic cells of the anterior pituitary. The levels of circulating hormones are controlled via negative feedback to the hypothalamus. Increased concentrations of the gonadotrophins are seen in ovarian failure in women, whether pathological or after the natural menopause.

High concentrations of FSH are seen in azoospermic men and LH is increased if testosterone secretion is decreased.

 

Patient Preparation

Samples from patients receiving high biotin doses (i.e. >5 mg/day) should be taken at least 8 hours post dose. Please inform the laboratory if the patient has been treated with monoclonal mouse antibodies or may have received them for diagnostic purposes.

Notes

None Given

Reference Range

FSH:

- 0.95 – 11.95 IU/L Males

- 3.03 – 8.08 IU/L Female: Follicular phase

- 1.38 – 5.47 IU/L Luteal phase

- 2.55 – 16.69 IU/L Female: at ovulation

- 26.72 – 133.41 IU/L post menopausal

(Source: Abbott Diagnostics)

Specifications

  • EQA Scheme?: Yes
  • EQA Status:

    NEQAS and WEQAS

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Protection of Personal Information – Laboratory Medicine comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

The Trust Laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital were awarded UKAS (United Kingdom Accreditation Service) accreditation to the internationally recognised ISO 15189 standard in May 2015. For a list of accredited tests and other information please visit the test database http://www.heftpathology.com/frontpage/test-database.html.
Tests not appearing on this scope are either under consideration or in the process of accreditation and so currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235

UKAS HEFT