Department

Referred Work
GANG

Preferred Sample Type

Ganglioside Antibodies

Suitable Specimen Types

  • Serum
2ml serum

Specimen Transport

First class mail

Sample Preparation

Turnaround Time

14 days

Sample Stability

Ganglioside Antibodies

General Information

Gangliosides are sialylated glycosphingolipids present in the outer membranes of many cells. The highest concentrations are found in the central and peripheral neuronal tissues. Autoantibodies to gangliosides have been demonstrated in many patients with peripheral neuropathies. The presence of antibodies has a direct contribution to the pathogenesis of the disorders and clinical status can be related to antibody titre. Both IgM and IgG antibodies are clinically useful although of limited disease specificity. They have limited diagnostic potential and are best used as circumstantial evidence to support a clinical diagnosis and to monitor disease activity.

Notes

None Given

Reference Range

Range provided by reference laboratory Normal range (IgG & IgM) <1/500

Specifications

  • EQA Scheme?: No
  • EQA Status:

    No EQA SCHEME Available

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Protection of Personal Information – Laboratory Medicine comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

The Trust Laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital were awarded UKAS (United Kingdom Accreditation Service) accreditation to the internationally recognised ISO 15189 standard in May 2015. For a list of accredited tests and other information please visit the test database http://www.heftpathology.com/frontpage/test-database.html.
Tests not appearing on this scope are either under consideration or in the process of accreditation and so currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235

UKAS HEFT