Oestrogens are responsible for the development of secondary female sex characteristics and are involved in the control of the female reproductive process.
Oestradiol levels are used to evaluate ovarian function and to help diagnose the cause of precocious puberty in girls (very early signs of puberty) and gynaecomastia in men. Its main use has been to help diagnose the reason for amenorrhoea (for example, to determine whether the cause is menopause, pregnancy, or a medical problem). In treatment of sub-fertility, repeated measurements are used to follow follicle development in the ovary in the days prior to in-vitro fertilisation. Oestradiol may also be used to monitor menopausal hormone replacement therapy, if given as 17-oestradiol by implant.
Please note, the drug Mifepristone may interfere/crossreact with the Abbott Oestradiol assay leading to falsely elevated results. This applies to patients currently being treated with or recently treated with the drug Mifepristone, and patients should be not tested for up to two weeks based on information available regarding Mifepristone’s bioavailability
Male: 92 - 161 pmol/L
|Postmenopausal not on HRT||<103|
|Postmenopausal on HRT||<528|
(Source: Abbott Diagnostics)
NEQAS and WEQAS
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